Organic Acids
Medchemexpress LLC Gln-AMS TFA | 99.85% | 588.47 | 50 MG
Gln-AMS (TFA) is a type Ia aminoacyl-tRNA synthetase (AARS) inhibitor. It specifically inhibits glutaminyl-tRNA synthetase (GlnRS) with a Ki of 1.32 μM. This product is intended for research use only.
- Inhibits glutaminyl-tRNA synthetase.
- High purity of 99.85%.
- Available in various quantities.
- Data sheet, COA, SDS, and handling instructions provided.
- Supported by customer reviews and publications.
Medchemexpress LLC Vasculotide TFA | 99.66% | 14000 (average) | 1 MG
Vasculotide TFA is an angiopoietin-1 mimetic that activates Tie-2, inducing its phosphorylation. It exhibits anti-inflammatory and anti-permeability effects, ameliorating endotoxin-induced endothelial barrier dysfunction and promoting angiogenesis in a mouse model of diabetic ulcer. It also protects mice from vascular leakage, reduces mortality in murine abdominal sepsis, and decreases microvascular leakage while improving microcirculatory perfusion in a rat model of hemorrhagic shock.
- Activates Tie-2 and induces its phosphorylation
- Exhibits anti-inflammatory and anti-permeability effects
- Promotes angiogenesis
- Protects against vascular leakage and reduces mortality in sepsis models
- Improves microcirculatory perfusion
- For research use only
Medchemexpress LLC Α-MSH (TFA) | 171869-93-5 | 98.5% | 25 MG
α-MSH TFA (α-Melanocyte-Stimulating Hormone TFA) is an endogenous neuropeptide that acts as a melanocortin receptor 4 (MC4R) agonist. It exhibits anti-inflammatory and antipyretic activities, being a post-translational derivative of pro-opiomelanocortin (POMC).
- Modulates CNS inflammation by acting directly on melanocortin receptors in glial cells.
- Modulates NFκB activation.
- Inhibits translocation of transcription factor κB to the nucleus.
- Effectively modulates inflammatory reactions when given systemically.
Medchemexpress LLC Cyclorasin 9A5 (TFA) | 1 MG
Cyclorasin 9A5 (TFA) from MedChemExpress is a laboratory chemical intended for research use only. It is presented as a solid and is stable under recommended storage conditions, emphasizing careful handling and storage to maintain its integrity.
- Stable under recommended storage
- Keep sealed in cool, well-ventilated area, away from direct sunlight and ignition
- Powder storage: -80°C for 2 years, -20°C for 1 year
- Solution storage: -80°C for 6 months, -20°C for 1 month
- Ships at room temperature (less than 2 weeks)
- Not classified as hazardous
- Requires personal protective equipment (safety goggles, gloves, impervious clothing, respirator)
- Ensure adequate ventilation, safety shower, and eye wash station
Medchemexpress LLC Cpn-267 Tfa | 1279.27 | 5 MG
CPN-267 (compound 7b) TFA is a highly selective agonist for neuromedin U receptor 1 (NMUR1), demonstrating an EC50 of 0.25 nM. This compound has been observed to inhibit body weight gain in mice, making it a valuable tool for research into obesity. It is designated strictly for research applications and is not for sale to patients.
- Selective neuromedin U receptor 1 (NMUR1) agonist
- EC50: 0.25 nM
- Suppresses body weight gain in mice
- Used for the study of obesity
Medchemexpress LLC LY117018 TFA 25mg | 2390041-98-0 | 25 MG
LY117018 TFA is a raloxifene analog and a selective estrogen receptor modulator (SERM) reported to exert antiproliferative effects on breast cancer cell lines. Supplied as a trifluoroacetate salt, the compound is provided as a small-scale research reagent for in vitro studies.
- Selective estrogen receptor modulator activity.
- Reported antiproliferative effects on breast cancer cell lines.
- Supplied as a trifluoroacetate salt for improved handling.
- Available in milligram-scale quantities for research use.
- Chemical formula C29H26F3NO6S; molecular weight 573.58 g/mol.
Medchemexpress LLC DV1 TFA | 98.5% | 2424.85 | 5 MG
DV1 TFA is a selective antagonist for CXC chemokine receptor 4 (CXCR4) and exhibits antiviral activity. This product is for research use only and has not been fully validated for medical applications.
- Selective antagonist for CXC chemokine receptor 4 (CXCR4)
- Exhibits antiviral activity
- For research use only
Medchemexpress LLC Ecallantide TFA | 9007-83-4 | 99.54% | 7053.81 | 50 MG
Ecallantide TFA is a specific recombinant plasma kallikrein inhibitor that works by inhibiting the production of bradykinin, thereby offering a potential treatment for acute attacks of angioedema.
- Specific recombinant plasma kallikrein inhibitor
- Inhibits the production of bradykinin
- May be used to prevent acute attacks of angioedema
Medchemexpress LLC GRL-1720 TFA | 2835511-03-8 | C16H12ClF3N2O4 | 5 MG
GRL-1720 TFA is a potent inhibitor of SARS-CoV-2 Mpro, exhibiting anti-SARS-CoV2 activity with an EC50 value of 15 μM. This compound has a molecular weight of 388.73 and appears as a solid, ranging from light brown to brown in color.
- High purity of 98.94%.
- Shipped at room temperature.
- Store at -20°C, sealed, away from moisture.
- In solution, stable for 6 months at -80°C or 1 month at -20°C with sealed storage, away from moisture.
Medchemexpress LLC KRFK TFA | 99.8% | 577.73 (free base) | 5 MG
KRFK TFA is a peptide derived from TSP-1 that activates TGF-β. It promotes TGF-β-mediated signaling and its downstream role, independently of thrombospondin (TSP) receptors like CD47 and CD36. KRFK TFA is used in research for chronic ocular surface inflammatory disorders.
- Activates TGF-β.
- Promotes TGF-β-mediated signaling.
- Acts independently of thrombospondin (TSP) receptors (CD47 and CD36).
- Can be used for chronic ocular surface inflammatory disorders research.
Medchemexpress LLC PZ703b trifluoroacetate | 98.6% | 1714.46 g/mol | C82H103ClF6N10O13S4 | 5 MG
PZ703b TFA is a Bcl-xL-targeting PROTAC degrader provided for laboratory research use. It induces rapid BCL-XL degradation, triggers caspase-3-mediated apoptosis, and inhibits cancer cell proliferation in vitro, including activity in bladder cancer models and hematologic cell lines. Supplied as a trifluoroacetate salt, it is intended for biochemical and cell-based studies only.
- Bcl-xL PROTAC degrader that promotes targeted protein degradation.
- Induces caspase-3-mediated apoptosis in susceptible cell lines.
- Inhibits cell proliferation and can act synergistically with other small-molecule inhibitors in vitro.
- Demonstrated low-nanomolar cellular potency in selected hematologic cell lines.
- High purity (>98%) suitable for biochemical and cell-based assays.
- Available in small milligram pack sizes for research use only.
Medchemexpress LLC RVG TFA | 99.3% | 3266.62 | 5 MG
RVG TFA is a peptide derived from Rabies Virus Glycoprotein. It binds to the α-7 subunit of nicotinic acetylcholine receptors (AchR) of neuronal cells and enhances the delivery of *Mycobacterium tuberculosis* antigens to antigen-presenting cells.
- Binds to α-7 subunit of nicotinic acetylcholine receptors
- Enhances delivery of *Mycobacterium tuberculosis* antigens
- Appears as a solid
- Color: white to off-white
- Soluble in water at ≥ 100 mg/mL
- For research use only
Medchemexpress LLC KS-133 (TFA) | 98.95% | 1672.93 | 1 MG
KS-133 TFA is a highly selective and potent antagonist of the vascular active enteropeptide receptor 2 (VIPR2). It reverses the tumor-promoting M2 phenotype of tumor-associated macrophages to the anti-tumor M1 phenotype, alters the tumor immune microenvironment, and inhibits tumor growth. It is suitable for research on schizophrenia and cancer immune regulation.
- Highly selective and potent VIPR2 antagonist
- IC50 values for Ca influx measurement: 24.8 nM; cAMP measurement: 500 nM
- Reverses M2 to M1 macrophage phenotype
- Alters tumor immune microenvironment and inhibits tumor growth
- Inhibits excessive VIPR2 activation, preventing cognitive impairments and neuronal damage
- Demonstrates anti-tumor activity and synergistic effects with anti-PD-1 antibodies
Medchemexpress LLC Gmprga Tfa | 98.1% | 5 MG
GMPRGA TFA is the trifluoroacetic acid (TFA) salt form of GMPRGA. It is known to recognize spAimR in the bacterial cytosol, a process that induces lysogeny.
- TFA salt form
- Recognizes spAimR in bacterial cytosol
- Induces lysogeny
- Functions as an inhibitor
- Part of bacterial lysis-lysogeny studies
- Classified as an antimicrobial peptide
Medchemexpress LLC Thymotrinan trifluoroacetate | 00-00-0 | 98.7% | 531.48 g·mol⁻¹ | C18H32F3N7O8 | 25 MG
Thymotrinan TFA is a biologically active fragment of the thymus hormone thymopoietin, provided as the trifluoroacetate (TFA) salt for research use. It modulates immune responses, affecting both humoral and cellular immunity, and is supplied as a purified synthetic peptide for laboratory studies.
- Immunomodulating peptide that affects humoral and cellular responses.
- Supplied as the trifluoroacetate salt for improved stability and handling.
- High purity suitable for in vitro and preclinical research.
- Available in small-scale quantities for peptide research workflows.
- Molecular weight 531.48 g·mol⁻¹; formula C18H32F3N7O8.